synthesis and antibacterial activity of silver-hydrogel nanocomposite containing antibiotics |
Paper ID : 1567-UFGNSM-FULL |
Authors: |
Abstract: |
Silver has been in use since time immemorial in the form of metallic silver, silver nitrate, for the treatment of burns, wounds and several bacterial infectionsn recent study, we report the synthesis and antibacterial activity of silver nanoparticles embedded in smart poly (N-isopropylacrylamide)-based hydrogel networks. A series of thermo-sensitive poly (N-isopropylacrylamide-methacrylic acid-hydroxyethyl methacrylate) [P( NIPAAm -MAA-HEM)] with various cross-linking ratio have been obtained by cross-linking free radical polymerization of N-isopropylacrylamide (NIPAAm), methacrylic acid (MAA) and hydroxyethyl methacrylate (HEM) in the presence of triethyleneglycol dimethacrylate (TEGDMA) as cross-linker. Highly stable and uniformly distributed silver nanoparticles have been obtained with hydrogel networks via in situ reduction of silver nitrate (AgNO3) using sodium borohydride (NaBH4) as reducing agent. The formation of silver nanoparticles has been confirmed with ultraviolet visible (UV–Vis) spectroscopy.The preliminary antibacterial activity performed to these hydrogel–silver nanocomposites. |
Keywords: |
Nanocomposite .Hydrogel, Silver nanoparticles, Antibacterial activity, Amoxicillin, Scanning electron microscopy |
Status : Paper Accepted (Poster Presentation) |